ABSTRACT
Background: Magnetic resonance enterography [MRE] has become the modality of choice in assessment of patients with Crohn's disease [CD]
We aimed to present our experience on 300 patients with CD who underwent MRE during the first 30 months after setting up MRE for the first time in a referral center in Iran
Methods: Patients with a definite diagnosis of CD based on either ileocolonoscopy or histopathological studies were included in the final report and categorized into four phenotypes of inactive, active, stricturing, and penetrating disease
Results: This was a case series study on 300 patients with known CD out of 594 referred subjects. The most prevalent phenotype was inactive observed in 162 [54.0%] patients followed by stricturing in 44 [14.7%], active in 40 [13.3%], penetrating in 27[9%], and active on chronic in 27 [9%] cases. The number of referred patients increased from 51 cases in the first 6 months to 165 in the last 6 months
Conclusion: This study presents the first report on the application of MRE in Iran as superb modality for management of CD. The growing number of referred patients indicates that MRE has been successful in addressing the most critical concerns of clinicians on determining the dominant disease phenotype
ABSTRACT
A young man presented with a large liver mass and positive hepatitis B virus markers. This 18-year-old male has developed ascites, jaundice, high serum alpha fetoprotein [AFP] level, liver mass and portal hypertension, without fever or calcification in the mass. All favored the diagnosis of rapidly, progressive hepatocellular carcinoma, however proven hepatoblastoma in liver biopsy. Hepatoblastoma usually manifests prior to the third year of life, but can rarely be seen in older children or adults. Although HCC rarely can be presented in young patients with HBV infection, but in patients without cirrhosis hepato-blastoma should be considered as the first possible diagnosis